Unlike THC, which primarily binds to CB-1 receptors located in the brain, CBD works in the body by manipulating receptors throughout organ tissues, the immune system, the pain response system, the hormonal system, and other whole-body regulatory systems. Basically, since its receptors have been found to exist in virtually every cell and tissue type in the body, CBD is believed to work on every aspect of human health and behavior – from the subcellular level to the whole-body leve and beyond.


The science behind CBD is in the relatively early stages. As a cannabinoid, we know that CBD interacts with receptors in your endocannabinoid system. The endocannabinoid system is integrated throughout your body — and this widespread, whole-body interaction creates a broad range of effects. Hence, the long list of possible benefits.   We may still be in the early stages of discovery, but there’s plenty of scientific studies and anecdotal evidence that CBD provides relief for an array of ailments. Here’s a non-exhaustive list of some potential benefits of CBD oil:
The key is to effectively gauge exactly how much CBD oil it takes to start managing your pain. If you start off right away with a maximum dose of a 600 mg tincture, you will have no idea how much of the product it actually took to treat your condition, and how much you wasted (this is also important because you do not want to exceed dosage and end up developing a tolerance to the active cannabinoids).
Cannabidiol, more commonly known as CBD, is one of 113 known cannabinoids found in cannabis. But unlike its better-known counterpart THC (tetrahydrocannabinol), responsible for cannabis’ mind-altering effects, extensive research suggests that CBD is not psychoactive, and with none of the often-damaging side effects accompanying synthetic pharmaceuticals.
People who experience psychosis may produce too much or even too little cannabinoids (from overactive dopamine receptors). CBD is milder than our internal cannabinoids and helps to re-establish a balance of cannabinoids in the brain. CBD also helps lower inflammation, which is often increased in schizophrenia. THC, on the other hand, is stronger than our internal cannabinoids (anandamide and 2-AG), this way potentially triggering psychosis [46, 48].
For some people, however, regular strength CBD just doesn’t cut it. If you’re one of those people, you may require something a lot stronger. If you think that CBD “doesn’t work”, then it’s possible that you might need to step it up to something stronger. Whether you’ll be good with a 1000mg high-strength CBD oil or if you need to step up to the big leagues with the Hemp Bombs 4000mg vape juice is a matter of personal preference. Everyone’s body is different. What works for someone else may not work for you. Experiment and find the perfect dosage that works best for your unique needs.
In one survey, parents of children who suffer from treatment-resistant epilepsy and use CBD were asked about the benefits. 19 parents were included, 84% of which said that CBD reduced the frequency of seizures. Two parents said that CBD completely resolved seizures. Parents also reported improved alertness, sleep, and mood. Some side effects were drowsiness and fatigue [54].
What you gain from Full Spectrum CBD is called the “entourage effect.” Studies have suggested that CBD is most effective when it’s combined with other cannabinoids. Each cannabinoid has its own properties and confers its own benefits. Working together, a synergy is created that boosts the healing properties of CBD. Full spectrum CBD does, however, bring with it the sticky issue of THC. The government regulates concentration levels of THC at 0.3 percent, an amount which results in minimal psychoactivity.
The interest and preference for botanical remedies such as CBD oil over harsh pharmaceuticals are growing rapidly. You can read scientific research on the promise of CBD Oil at NCBI. While North America is taking the lead legalizing cannabis and hemp the rest of the world is starting to question their stance on prohibition because of the undeniable benefits. While all talk about plant-based remedies may seem very new, using cannabis/hemp tinctures as a holistic remedy is a generations-old tradition. It was very common to use tinctures of cannabis oil in the eighteenth and nineteenth centuries. We are enjoying a renaissance in ancestral health where we are open again to remedies that were all but forgotten about in the mad race to make medicines a pill offered by a faceless often unaccountable corporation.
Although CBD oils aren’t regulated by the FDA, purchasing products stateside from one of the nine states where recreational and medical cannabis use is legal will likely result in a higher-quality product than buying one made with hemp-derived CBD oil imported from abroad, says Martin Lee, director of Project CBD, a nonprofit that promotes medical research into CBD.
Fill the dropper with the CBD oil, place the tip of the dropper under the tongue and drip in the desired amount. Let the CBD oil get adsorbed for 1-5 minutes before swallowing it. If you are having a hard time with the dosage or the number of drops when you drip it under your tongue, you can also use a spoon. Just put the desired amount of CBD oil on the spoon and try to put it under the tongue. Just lick off the remaining oil on the spoon. Due to the fine blood vessels and mucous membranes in the mouth, the CBD quickly enters the bloodstream and therefore has a good bioavailability.

Cannabidiol is the major nonpsychoactive component of Cannabis sativa. Over the centuries, a number of medicinal preparations derived from C. sativa have been employed for a variety of disorders, including gout, rheumatism, malaria, pain, and fever. These preparations were widely employed as analgesics by Western medical practitioners in the 19th century (1). More recently, there is clinical evidence suggesting efficacy in HIV-associated neuropathic pain, as well as spasms associated with multiple sclerosis (1).
CBD oil has numerous healing properties and has been connected to assisting with a diverse number of health problems. From migraines to anxiety and stress CBD oil is gaining popularity among medical patients. Only now is CBD oil coming into the light and thanks to this miraculous plant there are many ways you can use CBD oil, depending on what you want relief from!
Unfortunately due to the disappointing and down right inaccurate position of the federal government in classifying Cannabis as a schedule one drug, most research institutions risk federal funding if they conduct real research on Cannabis. This has dramatically limited the potential for real research by real scientists to be conducted. That research is critical to better understanding the multitude of therapeutic effects of the various chemical constituents found in Cannabis.

The furry subjects, 277 Wistar rats, were given a dose of CBD immediately after receiving a small electric shock. The CBD-treated subjects were found to spend less time frozen in fear when reintroduced to the context of the fearful event. This means the CBD disrupted consolidation (or more simply put: memory strengthening) of their specific and long-term fear memory.


It’s safe to say that Charlotte’s Web is probably the most recognized CBD brand out there — and it’s not all hype. This company pioneered the CBD industry and made it their mission to de-stigmatize CBD by setting the bar high for transparency. They produce and oversee their organic CBD products from seed to sale, standing behind them with a solid return policy. 
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